Genetically engineered mesenchymal stem cells with dopamine synthesis for Parkinson’s disease in animal models

Although striatal delivery of three critical genes for dopamine synthesis by viruses is a potential clinical approach for treating Parkinson’s disease (PD), the approach makes it difficult to finely control dopamine secretion amounts and brings safety concerns. Here, we generate genetically engineer...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jun, Li, Nan, Wei, Jingkuan, Feng, Chun, Chen, Yanying, Chen, Tingwei, Ai, Zongyong, Zhu, Xiaoqing, Ji, Weizhi, Li, Tianqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780305/
https://www.ncbi.nlm.nih.gov/pubmed/36550118
http://dx.doi.org/10.1038/s41531-022-00440-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780305/
https://www.ncbi.nlm.nih.gov/pubmed/36550118
http://dx.doi.org/10.1038/s41531-022-00440-6

Ejemplares similares