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Genetically engineered mesenchymal stem cells with dopamine synthesis for Parkinson’s disease in animal models

Although striatal delivery of three critical genes for dopamine synthesis by viruses is a potential clinical approach for treating Parkinson’s disease (PD), the approach makes it difficult to finely control dopamine secretion amounts and brings safety concerns. Here, we generate genetically engineer...

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Detalles Bibliográficos
Autores principales:	Li, Jun, Li, Nan, Wei, Jingkuan, Feng, Chun, Chen, Yanying, Chen, Tingwei, Ai, Zongyong, Zhu, Xiaoqing, Ji, Weizhi, Li, Tianqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780305/ https://www.ncbi.nlm.nih.gov/pubmed/36550118 http://dx.doi.org/10.1038/s41531-022-00440-6

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