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Role of eIF4A1 in triple‐negative breast cancer stem‐like cell‐mediated drug resistance
In cap‐dependent translation, the eukaryotic translation initiation factor 4A (eIF4A1) is an mRNA helicase is involved in unwinding of the secondary structure, such as the stem‐loops, at the 5′‐leader regions of the key oncogenic mRNAs. This facilitates ribosomal scanning and translation of the onco...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780423/ https://www.ncbi.nlm.nih.gov/pubmed/33053607 http://dx.doi.org/10.1002/cnr2.1299 |