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The paradigm shift: Heartbeat initiation without “the pacemaker cell”
The current dogma about the heartbeat origin is based on “the pacemaker cell,” a specialized cell residing in the sinoatrial node (SAN) that exhibits spontaneous diastolic depolarization triggering rhythmic action potentials (APs). Recent high-resolution imaging, however, demonstrated that Ca signal...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780451/ https://www.ncbi.nlm.nih.gov/pubmed/36569749 http://dx.doi.org/10.3389/fphys.2022.1090162 |