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Ophiopogonin D increase apoptosis by activating p53 via ribosomal protein L5 and L11 and inhibiting the expression of c-Myc via CNOT2

Ophiopogonin D (OP-D), which is extracted from the root tuber of Ophiopogon japonicus, is well known for its anti-inflammatory, anti-oxidant, and anti-cancer effects. It is also therapeutic for various diseases such as diabetic myocardial injuries, obesity, atopic dermatitis, and osteoporosis. Howev...

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Detalles Bibliográficos
Autores principales: Ko, Hyun Min, Jee, Wona, Lee, Duckgue, Jang, Hyeung-Jin, Jung, Ji Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780504/
https://www.ncbi.nlm.nih.gov/pubmed/36569330
http://dx.doi.org/10.3389/fphar.2022.974468