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Establishment and validation of a torsade de pointes prediction model based on human iPSC‑derived cardiomyocytes
Drug-induced cardiotoxicity is one of the main causes of drug failure, which leads to subsequent withdrawal from pharmaceutical development. Therefore, identifying the potential toxic candidate in the early stages of drug development is important. Human induced pluripotent stem cell-derived cardiomy...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780517/ https://www.ncbi.nlm.nih.gov/pubmed/36588805 http://dx.doi.org/10.3892/etm.2022.11760 |