A Phase 1 pharmacokinetic study of a single-dose bioadhesive clindamycin 2% gel for bacterial vaginosis

OBJECTIVES: To evaluate pharmacokinetics (PK) of a single dose of an investigational 2% clindamycin phosphate vaginal gel in healthy women by assessment of plasma and vaginal clindamycin concentrations over 7 days, and assess safety. METHODS: Single-centre, Phase 1, single-dose PK study. Blood and v...

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Detalles Bibliográficos
Autores principales: Mauck, Christine K, Atiee, George J, McCulloh, Jennifer, Reynolds, Laurie, Zack, Nadene, Friend, David R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780544/
https://www.ncbi.nlm.nih.gov/pubmed/36418189
http://dx.doi.org/10.1093/jac/dkac386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780544/
https://www.ncbi.nlm.nih.gov/pubmed/36418189
http://dx.doi.org/10.1093/jac/dkac386

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