The BLM helicase is a new therapeutic target in multiple myeloma involved in replication stress survival and drug resistance

Multiple myeloma (MM) is a hematologic cancer characterized by accumulation of malignant plasma cells in the bone marrow. To date, no definitive cure exists for MM and resistance to current treatments is one of the major challenges of this disease. The DNA helicase BLM, whose depletion or mutation c...

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Detalles Bibliográficos
Autores principales: Ovejero, Sara, Viziteu, Elena, Dutrieux, Laure, Devin, Julie, Lin, Yea-Lih, Alaterre, Elina, Jourdan, Michel, Basbous, Jihane, Requirand, Guilhem, Robert, Nicolas, de Boussac, Hugues, Seckinger, Anja, Hose, Dirk, Vincent, Laure, Herbaux, Charles, Constantinou, Angelos, Pasero, Philippe, Moreaux, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780552/
https://www.ncbi.nlm.nih.gov/pubmed/36569948
http://dx.doi.org/10.3389/fimmu.2022.983181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780552/
https://www.ncbi.nlm.nih.gov/pubmed/36569948
http://dx.doi.org/10.3389/fimmu.2022.983181

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