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Specific Zn(II)-binding site in the C-terminus of Aspf2, a zincophore from Aspergillus fumigatus

Aspergillus fumigatus, one of the most widespread opportunistic human fungal pathogens, adapts to zinc limitation by secreting a 310 amino acid Aspf2 zincophore, able to specifically bind Zn(II) and deliver it to a transmembrane zinc transporter, ZrfC. In this work, we focus on the thermodynamics of...

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Detalles Bibliográficos
Autores principales: Garstka, Kinga, Hecel, Aleksandra, Kozłowski, Henryk, Rowińska-Żyrek, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780748/
https://www.ncbi.nlm.nih.gov/pubmed/35700143
http://dx.doi.org/10.1093/mtomcs/mfac042