Loss of surface transport is a main cellular pathomechanism of CRB2 variants causing podocytopathies

Crumbs2 (CRB2) is a central component of the renal filtration barrier and part of the slit diaphragm, a unique cell contact formed by glomerular podocytes. Some CRB2 variants cause recessive inherited forms of steroid-resistant nephrotic syndrome. However, the disease-causing potential of numerous C...

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Detalles Bibliográficos
Autores principales: Möller-Kerutt, Annika, Schönhoff, Birgit, Rellmann, Yvonne, George, Britta, Braun, Daniela Anne, Pavenstädt, Hermann, Weide, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780758/
https://www.ncbi.nlm.nih.gov/pubmed/36549870
http://dx.doi.org/10.26508/lsa.202201649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780758/
https://www.ncbi.nlm.nih.gov/pubmed/36549870
http://dx.doi.org/10.26508/lsa.202201649

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