Immunoregulatory Sertoli Cell Allografts Engineered to Express Human Insulin Survive Humoral-Mediated Rejection

An effective treatment and possible cure for type 1 diabetes is transplantation of pancreatic islets. Unfortunately, transplanted islets are rejected by the immune system with humoral-mediated responses being an important part of rejection. Sertoli cells (SC), an immune regulatory cell shown to surv...

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Detalles Bibliográficos
Autores principales: Washburn, Rachel L., Hibler, Taylor, Kaur, Gurvinder, Sabu-Kurian, Anna, Landefeld, Alissa, Dufour, Jannette M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780793/
https://www.ncbi.nlm.nih.gov/pubmed/36555540
http://dx.doi.org/10.3390/ijms232415894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780793/
https://www.ncbi.nlm.nih.gov/pubmed/36555540
http://dx.doi.org/10.3390/ijms232415894

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