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Combining mKate2-Kv1.3 Channel and Atto488-Hongotoxin for the Studies of Peptide Pore Blockers on Living Eukaryotic Cells

The voltage-gated potassium Kv1.3 channel is an essential component of vital cellular processes which is also involved in the pathogenesis of some autoimmune, neuroinflammatory and oncological diseases. Pore blockers of the Kv1.3 channel are considered as potential drugs and are used to study Kv1 ch...

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Detalles Bibliográficos
Autores principales: Orlov, Nikita A., Ignatova, Anastasia A., Kryukova, Elena V., Yakimov, Sergey A., Kirpichnikov, Mikhail P., Nekrasova, Oksana V., Feofanov, Alexey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780825/
https://www.ncbi.nlm.nih.gov/pubmed/36548755
http://dx.doi.org/10.3390/toxins14120858