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Regeneration of Osteochondral Defects by Combined Delivery of Synovium-Derived Mesenchymal Stem Cells, TGF-β1 and BMP-4 in Heparin-Conjugated Fibrin Hydrogel

The regeneration of cartilage and osteochondral defects remains one of the most challenging clinical problems in orthopedic surgery. Currently, tissue-engineering techniques based on the delivery of appropriate growth factors and mesenchymal stem cells (MSCs) in hydrogel scaffolds are considered as...

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Detalles Bibliográficos
Autores principales: Sarsenova, Madina, Raimagambetov, Yerik, Issabekova, Assel, Karzhauov, Miras, Kudaibergen, Gulshakhar, Akhmetkarimova, Zhanar, Batpen, Arman, Ramankulov, Yerlan, Ogay, Vyacheslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780905/
https://www.ncbi.nlm.nih.gov/pubmed/36559710
http://dx.doi.org/10.3390/polym14245343