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Guanosine Prevents Spatial Memory Impairment and Hippocampal Damage Following Amyloid-β(1–42) Administration in Mice

Alzheimer’s disease (AD) is a progressive neurodegenerative illness responsible for cognitive impairment and dementia. Accumulation of amyloid-beta (Aβ) peptides in neurons and synapses causes cell metabolism to unbalance, and the production of reactive oxygen species (ROS), leading to neuronal deat...

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Detalles Bibliográficos
Autores principales: Coelho, Victor, Binder, Luisa Bandeira, Marques, Naiani Ferreira, Constantino, Leandra Celso, Mancini, Gianni, Tasca, Carla Inês
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780960/
https://www.ncbi.nlm.nih.gov/pubmed/36557245
http://dx.doi.org/10.3390/metabo12121207