Cognate RNA-Binding Modes by the Alternative-Splicing Regulator MBNL1 Inferred from Molecular Dynamics

The muscleblind-like protein family (MBNL) plays a prominent role in the regulation of alternative splicing. Consequently, the loss of MBNL function resulting from sequestration by RNA hairpins triggers the development of a neuromuscular disease called myotonic dystrophy (DM). Despite the sequence a...

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Detalles Bibliográficos
Autores principales: González, Àlex L., Fernández-Remacha, Daniel, Borrell, José Ignacio, Teixidó, Jordi, Estrada-Tejedor, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780971/
https://www.ncbi.nlm.nih.gov/pubmed/36555788
http://dx.doi.org/10.3390/ijms232416147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780971/
https://www.ncbi.nlm.nih.gov/pubmed/36555788
http://dx.doi.org/10.3390/ijms232416147

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