In Silico Drug Repurposing Framework Predicts Repaglinide, Agomelatine and Protokylol as TRPV1 Modulators with Analgesic Activity

Pain is one of the most common symptoms experienced by patients. The use of current analgesics is limited by low efficacy and important side effects. Transient receptor potential vanilloid-1 (TRPV1) is a non-selective cation channel, activated by capsaicin, heat, low pH or pro-inflammatory agents. S...

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Detalles Bibliográficos
Autores principales: Andrei, Corina, Mihai, Dragos Paul, Zanfirescu, Anca, Nitulescu, George Mihai, Negres, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781017/
https://www.ncbi.nlm.nih.gov/pubmed/36559057
http://dx.doi.org/10.3390/pharmaceutics14122563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781017/
https://www.ncbi.nlm.nih.gov/pubmed/36559057
http://dx.doi.org/10.3390/pharmaceutics14122563

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