Anti-Mycobacterial N-(2-Arylethyl)quinolin-3-amines Inspired by Marine Sponge-Derived Alkaloid

The synthesis and evaluation of simplified analogs of marine sponge-derived alkaloid 3-(phenethylamino)demethyl(oxy)aaptamine were performed to develop novel anti-mycobacterial substances. Ring truncation of the tricyclic benzo[de][1,6]-naphthyridine skeleton effectively weakened the cytotoxicity of...

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Detalles Bibliográficos
Autores principales: Mukomura, Junya, Nonaka, Hiroki, Sato, Hiromasa, Kishimoto, Maho, Arai, Masayoshi, Kotoku, Naoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781020/
https://www.ncbi.nlm.nih.gov/pubmed/36557834
http://dx.doi.org/10.3390/molecules27248701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781020/
https://www.ncbi.nlm.nih.gov/pubmed/36557834
http://dx.doi.org/10.3390/molecules27248701

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