Mitigating Cardiotoxicity of Dendrimers: Angiotensin-(1-7) via Its Mas Receptor Ameliorates PAMAM-Induced Cardiac Dysfunction in the Isolated Mammalian Heart

Aim: The influence of the physiochemical properties of dendrimer nanoparticles on cardiac contractility and hemodynamics are not known. Herein, we investigated (a) the effect of polyamidoamine (PAMAM) dendrimer generation (G7, G6, G5, G4 and G3) and surface chemistry (-NH(2), -COOH and -OH) on cardi...

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Detalles Bibliográficos
Autores principales: Akhtar, Saghir, Babiker, Fawzi, Akhtar, Usman A., Benter, Ibrahim F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781033/
https://www.ncbi.nlm.nih.gov/pubmed/36559167
http://dx.doi.org/10.3390/pharmaceutics14122673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781033/
https://www.ncbi.nlm.nih.gov/pubmed/36559167
http://dx.doi.org/10.3390/pharmaceutics14122673

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