Allylamines, Benzylamines, and Fungal Cell Permeability: A Review of Mechanistic Effects and Usefulness against Fungal Pathogens

Allylamines, naftifine and terbinafine, and the benzylamine, butenafine, are antifungal agents with activity on the fungal cell membrane. These synthetic compounds specifically inhibit squalene epoxidase, a key enzyme in fungal sterol biosynthesis. This results in a deficiency in ergosterol, a major...

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Detalles Bibliográficos
Autores principales: Hammoudi Halat, Dalal, Younes, Samar, Mourad, Nisreen, Rahal, Mohamad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781035/
https://www.ncbi.nlm.nih.gov/pubmed/36557078
http://dx.doi.org/10.3390/membranes12121171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781035/
https://www.ncbi.nlm.nih.gov/pubmed/36557078
http://dx.doi.org/10.3390/membranes12121171

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