New 5-Aryl-1,3,4-Thiadiazole-Based Anticancer Agents: Design, Synthesis, In Vitro Biological Evaluation and In Vivo Radioactive Tracing Studies

A new series of 5-(4-chlorophenyl)-1,3,4-thiadiazole-based compounds featuring pyridinium (3), substituted piperazines (4a–g), benzyl piperidine (4i), and aryl aminothiazoles (5a–e) heterocycles were synthesized. Evaluation of the cytotoxicity potential of the new compounds against MCF-7 and HepG2 c...

Descripción completa

Detalles Bibliográficos
Autores principales: El-Masry, Rana M., Essa, Basma M., Selim, Adli A., El-Emam, Soad Z., Mohamed, Khaled O., Sakr, Tamer M., Kadry, Hanan H., Taher, Azza T., Abou-Seri, Sahar M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781117/
https://www.ncbi.nlm.nih.gov/pubmed/36558927
http://dx.doi.org/10.3390/ph15121476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781117/
https://www.ncbi.nlm.nih.gov/pubmed/36558927
http://dx.doi.org/10.3390/ph15121476

Ejemplares similares