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New 5-Aryl-1,3,4-Thiadiazole-Based Anticancer Agents: Design, Synthesis, In Vitro Biological Evaluation and In Vivo Radioactive Tracing Studies

A new series of 5-(4-chlorophenyl)-1,3,4-thiadiazole-based compounds featuring pyridinium (3), substituted piperazines (4a–g), benzyl piperidine (4i), and aryl aminothiazoles (5a–e) heterocycles were synthesized. Evaluation of the cytotoxicity potential of the new compounds against MCF-7 and HepG2 c...

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Detalles Bibliográficos
Autores principales:	El-Masry, Rana M., Essa, Basma M., Selim, Adli A., El-Emam, Soad Z., Mohamed, Khaled O., Sakr, Tamer M., Kadry, Hanan H., Taher, Azza T., Abou-Seri, Sahar M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781117/ https://www.ncbi.nlm.nih.gov/pubmed/36558927 http://dx.doi.org/10.3390/ph15121476

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