Cargando…

Oligomer Formation by Amyloid-β42 in a Membrane-Mimicking Environment in Alzheimer’s Disease

The brains of Alzheimer’s disease (AD) patients contain numerous amyloid plaques that are diagnostic of the disease. The plaques are primarily composed of the amyloidogenic peptides proteins Aβ40 and Aβ42, which are derived by the processing of the amyloid pre-cursor protein (APP) by two proteases c...

Descripción completa

Detalles Bibliográficos
Autores principales: Rosenberry, Terrone L., Zhou, Huan-Xiang, Stagg, Scott M., Paravastu, Anant K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781152/
https://www.ncbi.nlm.nih.gov/pubmed/36557940
http://dx.doi.org/10.3390/molecules27248804