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Dorsolateral Prefrontal Cortex Glutamate/Gamma-Aminobutyric Acid (GABA) Alterations in Clinical High Risk and First-Episode Schizophrenia: A Preliminary 7-T Magnetic Resonance Spectroscopy Imaging Study

Converging lines of evidence suggest that an imbalance between excitation and inhibition is present in the dorsolateral prefrontal cortex (DLPFC) of schizophrenia (SCZ). Gamma-aminobutyric-acid (GABA) and, to a lesser extent, glutamate (Glu) abnormalities were reported in the DLPFC of SCZ patients,...

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Detalles Bibliográficos
Autores principales: Mayeli, Ahmad, Sonnenschein, Susan F., Yushmanov, Victor E., Wilson, James D., Blazer, Annie, Foran, William, Perica, Maria, Calabro, Finnegan J., Luna, Beatriz, Hetherington, Hoby P., Sarpal, Deepak K., Ferrarelli, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781166/
https://www.ncbi.nlm.nih.gov/pubmed/36555487
http://dx.doi.org/10.3390/ijms232415846