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2-Arylpropionic Acid Pyrazolamides as Cannabinoid CB2 Receptor Inverse Agonists Endowed with Anti-Inflammatory Properties

Among the most recent proposals regarding the mechanism of action of dipyrone, the modulation of cannabinoid receptors CB(1) and CB(2) appears to be a promising hypothesis. In this context, the present work describes a series of five novel pyrazolamides (7–11) designed as molecular hybrids of dipyro...

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Detalles Bibliográficos
Autores principales: de Oliveira, Daniela R., Maia, Rodolfo C., de Carvalho França, Patrícia R., Fernandes, Patrícia D., Barbosa, Gisele, Lima, Lídia M., Fraga, Carlos A. Manssour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781268/
https://www.ncbi.nlm.nih.gov/pubmed/36558970
http://dx.doi.org/10.3390/ph15121519