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2-Arylpropionic Acid Pyrazolamides as Cannabinoid CB2 Receptor Inverse Agonists Endowed with Anti-Inflammatory Properties
Among the most recent proposals regarding the mechanism of action of dipyrone, the modulation of cannabinoid receptors CB(1) and CB(2) appears to be a promising hypothesis. In this context, the present work describes a series of five novel pyrazolamides (7–11) designed as molecular hybrids of dipyro...
Autores principales: | de Oliveira, Daniela R., Maia, Rodolfo C., de Carvalho França, Patrícia R., Fernandes, Patrícia D., Barbosa, Gisele, Lima, Lídia M., Fraga, Carlos A. Manssour |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781268/ https://www.ncbi.nlm.nih.gov/pubmed/36558970 http://dx.doi.org/10.3390/ph15121519 |
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