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Longevity and Mechanism of Heterosubtypic Protection Induced by M2SR (M2-Deficient Single-Replication) Live Influenza Virus Vaccine in Mice

Seasonal influenza and the threat of global pandemics present a continuing threat to public health. However, conventional inactivated influenza vaccines (IAVs) provide little cross-protective immunity and suboptimal efficacy, even against well-matched strains. Furthermore, the protection against mat...

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Detalles Bibliográficos
Autores principales: Sarawar, Sally, Gabaglia, Claudia R., Sanchez, Adriana, Hatta, Yasuko, Dias, Peter, Neumann, Gabriele, Kawaoka, Yoshihiro, Bilsel, Pamuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781428/
https://www.ncbi.nlm.nih.gov/pubmed/36560540
http://dx.doi.org/10.3390/vaccines10122131