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ATL I, Acts as a SIRT6 Activator to Alleviate Hepatic Steatosis in Mice via Suppression of NLRP3 Inflammasome Formation

Accumulating evidence has highlighted that sirtuin-6 (SIRT6) plays an important role in hepatic gluconeogenesis and lipogenesis. We aim to investigate the underlying mechanisms and pharmacological interventions of SIRT6 on hepatic steatosis treatment. Herein, our results showed that atractylenolide...

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Detalles Bibliográficos
Autores principales: Kong, Danli, Mai, Zhenhua, Chen, Yongze, Luo, Ling, Liu, Hao, Zhao, Le, Huang, Ruixian, Wang, Shuang, Chen, Rong, Zhou, Hao, Chen, Hao, Zhang, Jingjing, Yu, Haibing, Ding, Yuanlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781479/
https://www.ncbi.nlm.nih.gov/pubmed/36558977
http://dx.doi.org/10.3390/ph15121526