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ATL I, Acts as a SIRT6 Activator to Alleviate Hepatic Steatosis in Mice via Suppression of NLRP3 Inflammasome Formation
Accumulating evidence has highlighted that sirtuin-6 (SIRT6) plays an important role in hepatic gluconeogenesis and lipogenesis. We aim to investigate the underlying mechanisms and pharmacological interventions of SIRT6 on hepatic steatosis treatment. Herein, our results showed that atractylenolide...
Autores principales: | Kong, Danli, Mai, Zhenhua, Chen, Yongze, Luo, Ling, Liu, Hao, Zhao, Le, Huang, Ruixian, Wang, Shuang, Chen, Rong, Zhou, Hao, Chen, Hao, Zhang, Jingjing, Yu, Haibing, Ding, Yuanlin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781479/ https://www.ncbi.nlm.nih.gov/pubmed/36558977 http://dx.doi.org/10.3390/ph15121526 |
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