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A Bioluminescence-Based Ex Vivo Burn Wound Model for Real-Time Assessment of Novel Phage-Inspired Enzybiotics

The silent pandemic of antibiotic resistance is thriving, prompting the urgent need for the development of new antibacterial drugs. However, within the preclinical pipeline, in vitro screening conditions can differ significantly from the final in vivo settings. To bridge the gap between in vitro and...

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Detalles Bibliográficos
Autores principales: De Maesschalck, Vincent, Gutiérrez, Diana, Paeshuyse, Jan, Briers, Yves, Vande Velde, Greetje, Lavigne, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781546/
https://www.ncbi.nlm.nih.gov/pubmed/36559047
http://dx.doi.org/10.3390/pharmaceutics14122553