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Anti-Tumor Effects of Engineered VNP20009-Abvec-Igκ-mPD-1 Strain in Melanoma Mice via Combining the Oncolytic Therapy and Immunotherapy

Programmed cell death protein 1/Programmed cell death ligand 1 (PD-1/PD-L1) immune checkpoint inhibitors are the most promising treatments for malignant tumors currently, but the low response rate limits their further clinical utilization. To address this problem, our group constructed an engineered...

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Detalles Bibliográficos
Autores principales: Zhou, De-Xi, Wang, Xiao-He, Xu, Xuan, Chen, Wen-Jie, Wei, Jing, Chen, Ting-Tao, Wei, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781615/
https://www.ncbi.nlm.nih.gov/pubmed/36559282
http://dx.doi.org/10.3390/pharmaceutics14122789