Dinuclear Iron Complexes of Iminopyridine-Based Ligands as Selective Cytotoxins for Tumor Cells and Inhibitors of Cancer Cell Migration

A family of dinuclear iron (II) compounds with iminopyridine-based ligands displays selective cytotoxic activity against cancer cell lines. All compounds have IC(50) values 2–6 fold lower than that of cisplatin, and 30–90 fold lower than that of carboplatin for the tumor cell lines assayed. Comparin...

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Detalles Bibliográficos
Autores principales: Castro, Jessica, Bravo, Marlon, Albertí, Meritxell, Marsal, Anaís, Alonso-De Gennaro, María José, Martínez-Ferraté, Oriol, Claver, Carmen, van Leeuwen, Piet W. N. M., Romero, Isabel, Benito, Antoni, Vilanova, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781652/
https://www.ncbi.nlm.nih.gov/pubmed/36559294
http://dx.doi.org/10.3390/pharmaceutics14122801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781652/
https://www.ncbi.nlm.nih.gov/pubmed/36559294
http://dx.doi.org/10.3390/pharmaceutics14122801

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