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Investigation of 1,4-Substituted 1,2,3-Triazole Derivatives as Antiarrhythmics: Synthesis, Structure, and Properties

Here, we investigated the reaction of 1,3-dipolar cycloaddition of 1,3-diazido-2-nitro-2- azapropane (DANP) to propargyl alcohol over a copper-based catalyst and identified the optimum reaction conditions that enable the synthesis of 2-nitro-1,3-bis(4,4′-dihydroxymethyl)-1,2,3-triazolyl-2-azapropane...

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Detalles Bibliográficos
Autores principales: Shestakova, Elena O., Il’yasov, Sergey G., Shchurova, Irina A., Glukhacheva, Vera S., Il’yasov, Dmitri S., Zhukov, Egor E., Bryzgalov, Arkady O., Tolstikova, Tatiana G., Gatilov, Yuri V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781658/
https://www.ncbi.nlm.nih.gov/pubmed/36558894
http://dx.doi.org/10.3390/ph15121443