Chemistry of Therapeutic Oligonucleotides That Drives Interactions with Biomolecules

Oligonucleotide therapeutics that can modulate gene expression have been gradually developed for clinical applications over several decades. However, rapid advances have been made in recent years. Artificial nucleic acid technology has overcome many challenges, such as (1) poor target affinity and s...

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Detalles Bibliográficos
Autores principales: Terada, Chisato, Kawamoto, Seiya, Yamayoshi, Asako, Yamamoto, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781680/
https://www.ncbi.nlm.nih.gov/pubmed/36559141
http://dx.doi.org/10.3390/pharmaceutics14122647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781680/
https://www.ncbi.nlm.nih.gov/pubmed/36559141
http://dx.doi.org/10.3390/pharmaceutics14122647

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