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2,5-Bis(2,2,2-trifluoroethoxy)phenyl-tethered 1,3,4-Oxadiazoles Derivatives: Synthesis, In Silico Studies, and Biological Assessment as Potential Candidates for Anti-Cancer and Anti-Diabetic Agent

In the present work, a series of new 1-{5-[2,5-bis(2,2,2-trifluoroethoxy)phenyl]-1,3,4-oxadiazol-3-acetyl-2-aryl-2H/methyl derivatives were synthesized through a multistep reaction sequence. The compounds were synthesized by the condensation of various aldehydes and acetophenones with the laboratory...

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Detalles Bibliográficos
Autores principales: Shankara, Sathyanarayana D., Isloor, Arun M., Kudva, Avinash K., Raghu, Shamprasad Varija, Jayaswamy, Pavan K., Venugopal, Pushyaraga P., Shetty, Praveenkumar, Chakraborty, Debashree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781914/
https://www.ncbi.nlm.nih.gov/pubmed/36557829
http://dx.doi.org/10.3390/molecules27248694