The Insulin-like Growth Factor Signaling Pathway in Breast Cancer: An Elusive Therapeutic Target

In this review, we provide an overview of the role of the insulin-like growth factor (IGF) signaling pathway in breast cancer and discuss its potential as a therapeutic target. The IGF pathway ligands, IGF-1 and IGF-2, and their receptors, primarily IGF-1R, are important for normal mammary gland bio...

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Detalles Bibliográficos
Autores principales: Lee, Ji-Sun, Tocheny, Claire E., Shaw, Leslie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782138/
https://www.ncbi.nlm.nih.gov/pubmed/36556357
http://dx.doi.org/10.3390/life12121992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782138/
https://www.ncbi.nlm.nih.gov/pubmed/36556357
http://dx.doi.org/10.3390/life12121992

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