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Antiproliferative Activity of Buddleja saligna (Willd.) against Melanoma and In Vivo Modulation of Angiogenesis

Melanoma cells secrete pro-angiogenic factors, which stimulates growth, proliferation and metastasis, and therefore are key therapeutic targets. Buddleja saligna (BS), and an isolated triterpenoid mixture (DT-BS-01) showed a fifty percent inhibitory concentration (IC(50)) of 33.80 ± 1.02 and 5.45 ±...

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Detalles Bibliográficos
Autores principales: Twilley, Danielle, Thipe, Velaphi C., Kishore, Navneet, Bloebaum, Pierce, Roma-Rodrigues, Catarina, Baptista, Pedro V., Fernandes, Alexandra R., Selepe, Mamoalosi A., Langhansova, Lenka, Katti, Kattesh, Lall, Namrita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782150/
https://www.ncbi.nlm.nih.gov/pubmed/36558948
http://dx.doi.org/10.3390/ph15121497