Cargando…

Isotopic Radiolabeling of Crizotinib with Fluorine-18 for In Vivo Pet Imaging

Crizotinib is a tyrosine kinase inhibitor approved for the treatment of non-small-cell lung cancer, but it is inefficient on brain metastases. Crizotinib is a substrate of the P-glycoprotein, and non-invasive nuclear imaging can be used to assess the brain penetration of crizotinib. Positron emissio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sardana, Malvika, Breuil, Louise, Goutal, Sébastien, Goislard, Maud, Kondrashov, Mikhail, Marchal, Etienne, Besson, Florent L., Dugave, Christophe, Wrigley, Gail, Jonson, Anna C., Kuhnast, Bertrand, Schou, Magnus, Tournier, Nicolas, Elmore, Charles S., Caillé, Fabien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782192/ https://www.ncbi.nlm.nih.gov/pubmed/36559018 http://dx.doi.org/10.3390/ph15121568

Ejemplares similares

Isotopic Radiolabeling of the Antiretroviral Drug [(18)F]Dolutegravir for Pharmacokinetic PET Imaging
por: Tisseraud, Marion, et al.
Publicado: (2022)

Comparison of the Blood–Brain Barrier Transport and Vulnerability to P-Glycoprotein-Mediated Drug–Drug Interaction of Domperidone versus Metoclopramide Assessed Using In Vitro Assay and PET Imaging
por: Breuil, Louise, et al.
Publicado: (2022)

Visible-Light-Enabled Aminocarbonylation of Unactivated Alkyl Iodides with Stoichiometric Carbon Monoxide for Application on Late-Stage Carbon Isotope Labeling
por: Sardana, Malvika, et al.
Publicado: (2019)

Validation of a pharmacological imaging challenge using (11)C-buprenorphine and (18)F-2-fluoro-2-deoxy-D-glucose positron emission tomography to study the effects of buprenorphine to the rat brain
por: Soyer, Amélie, et al.
Publicado: (2023)

Impact of Cytochrome Induction or Inhibition on the Plasma and Brain Kinetics of [(11)C]metoclopramide, a PET Probe for P-Glycoprotein Function at the Blood-Brain Barrier
por: Breuil, Louise, et al.
Publicado: (2022)

Positron Emission Tomography Imaging Reveals an Importance of Saturable Liver Uptake Transport for the Pharmacokinetics of Metoclopramide
por: Caillé, Fabien, et al.
Publicado: (2018)

Pharmacokinetic Imaging Using (99m)Tc-Mebrofenin to Untangle the Pattern of Hepatocyte Transporter Disruptions Induced by Endotoxemia in Rats
por: Marie, Solène, et al.
Publicado: (2022)

New trends and applications in carboxylation for isotope chemistry
por: Bragg, Ryan A., et al.
Publicado: (2018)

Recent Trends in Bioorthogonal Click-Radiolabeling Reactions Using Fluorine-18
por: Pretze, Marc, et al.
Publicado: (2013)

Exploring the enzyme‐catalyzed synthesis of isotope labeled cyclopropanes
por: Sardana, Malvika, et al.
Publicado: (2022)

[(18)F]2-Fluoro-2-deoxy-sorbitol PET Imaging for Quantitative Monitoring of Enhanced Blood-Brain Barrier Permeability Induced by Focused Ultrasound
por: Hugon, Gaëlle, et al.
Publicado: (2021)

Impact of rifampicin-inhibitable transport on the liver distribution and tissue kinetics of erlotinib assessed with PET imaging in rats
por: Amor, Dorra, et al.
Publicado: (2018)

Development of a fluorine-18 radiolabelled fluorescent chalcone: evaluated for detecting glycogen
por: Allott, Louis, et al.
Publicado: (2020)

Synthesis, Fluorine-18 Radiolabeling, and In Vivo PET Imaging of a Hydrophilic Fluorosulfotetrazine
por: Beaufrez, Jason, et al.
Publicado: (2023)

Late‐Stage Isotopic Carbon Labeling of Pharmaceutically Relevant Cyclic Ureas Directly from CO(2)
por: Del Vecchio, Antonio, et al.
Publicado: (2018)

Preclinical evaluation of carbon-11 and fluorine-18 sulfonamide derivatives for in vivo radiolabeling of erythrocytes
por: Gheysens, Olivier, et al.
Publicado: (2013)

Impact of Donepezil on Brain Glucose Metabolism Assessed Using [(18)F]2-Fluoro-2-deoxy-D-Glucose Positron Emission Tomography Imaging in a Mouse Model of Alzheimer’s Disease Induced by Intracerebroventricular Injection of Amyloid-Beta Peptide
por: Hugon, Gaëlle, et al.
Publicado: (2022)

Acute Morphine Exposure Increases the Brain Distribution of [(18)F]DPA-714, a PET Biomarker of Glial Activation in Nonhuman Primates
por: Auvity, Sylvain, et al.
Publicado: (2016)

Three-dimensional spatiotemporal tracking of fluorine-18 radiolabeled yeast cells via positron emission particle tracking
por: Langford, Seth T., et al.
Publicado: (2017)

Radiolabeling and in vivo evaluation of lanmodulin with biomedically relevant lanthanide isotopes
por: Martin, Kirsten E., et al.
Publicado: (2023)

Correction: Radiolabeling and in vivo evaluation of lanmodulin with biomedically relevant lanthanide isotopes
por: Martin, Kirsten E., et al.
Publicado: (2023)

Radiolabeled Bombesin Analogs
por: Mansi, Rosalba, et al.
Publicado: (2021)

Radiolabeled PSMA Inhibitors
por: Neels, Oliver C., et al.
Publicado: (2021)

Towards laser spectroscopy of exotic fluorine isotopes
por: Garcia Ruiz, Ronald Fernando
Publicado: (2016)

Dual-isotope imaging allows in vivo immunohistochemistry using radiolabelled antibodies in tumours()()
por: Knight, James C., et al.
Publicado: (2019)

Crizotinib: A comprehensive review
por: Sahu, Arvind, et al.
Publicado: (2013)

Crizotinib: Pneumonitis: case report
Publicado: (2021)

Radioactivity of neutron rich oxygen, fluorine and neon isotopes
por: Reed, A T, et al.
Publicado: (1999)

Successful Desensitization with Crizotinib after Crizotinib-induced Liver Injury in ROS1-rearranged Lung Adenocarcinoma
por: Ota, Takayo, et al.
Publicado: (2019)

Radiolabelled peptides for oncological diagnosis
por: Laverman, Peter, et al.
Publicado: (2012)

Targeting telomerase with radiolabeled inhibitors
por: Waghorn, Philip A., et al.
Publicado: (2017)

Radiolabeled Peptides and Antibodies in Medicine
por: Kręcisz, Paweł, et al.
Publicado: (2020)

Radiolabeling of Nanomaterials: Advantages and Challenges
por: Dai, Wanqin, et al.
Publicado: (2021)

Abnormal Expression of Synaptic and Extrasynaptic GABA(A) Receptor Subunits in the Dystrophin-Deficient mdx Mouse
por: Zarrouki, Faouzi, et al.
Publicado: (2022)

Crizotinib targets in glioblastoma stem cells
por: Junca, Audelaure, et al.
Publicado: (2017)

Crizotinib-induced Rectal Perforation with Abscess
por: Yanagisawa, Asako, et al.
Publicado: (2017)

Efficacy of crizotinib retreatment after crizotinib-related interstitial lung disease in a patient with ROS1-rearranged advanced lung adenocarcinoma: A case report and potential crizotinib retreatment strategy
por: Ryu, Woo Kyung, et al.
Publicado: (2022)

The Activity of Crizotinib in Chemo-Refractory MET-Amplified Esophageal and Gastric Adenocarcinomas: Results from the AcSé-Crizotinib Program
por: Aparicio, Thomas, et al.
Publicado: (2021)

Targeting prostate cancer with radiolabelled bombesins
por: Maina, Theodosia, et al.
Publicado: (2006)

Synthesis and radiolabeling of heterocyclic food mutagens.
por: Rapoport, H, et al.
Publicado: (1986)

Cannot write session to /tmp/vufind_sessions/sess_o6es8hdm49qqu9lpl02cl70s00