Preliminary Assessment of Intramuscular Depot of Lipid-Based Decoquinate Formulation for Long-Term Chemoprophylaxis of Malaria

Sustained-release formulations of decoquinate were evaluated for the long-term prophylaxis of malaria. In the initial experiment, mice were protected from liver-stage Plasmodium infection by intramuscular administration of a lipids-based formulation at a dose of decoquinate 200 mg/kg. The mice that...

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Detalles Bibliográficos
Autores principales: Fan, Yinzhou, Qin, Li, Huang, Zhenping, Liang, Shuanghong, Huang, Xiaoyi, Zeng, Sumei, Liu, Yucheng, Wang, Hongxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782194/
https://www.ncbi.nlm.nih.gov/pubmed/36559304
http://dx.doi.org/10.3390/pharmaceutics14122813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782194/
https://www.ncbi.nlm.nih.gov/pubmed/36559304
http://dx.doi.org/10.3390/pharmaceutics14122813

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