Enhanced Nasal Deposition and Anti-Coronavirus Effect of Favipiravir-Loaded Mucoadhesive Chitosan–Alginate Nanoparticles

Favipiravir (FVR) is a repurposed antiviral drug for treating mild to moderate cases of the novel coronavirus disease 2019 (COVID-19). However, its poor solubility and permeability limit its clinical efficacy. To overcome its physicochemical and pharmacokinetic limitations, we statistically designed...

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Detalles Bibliográficos
Autores principales: Alcantara, Khent Primo, Nalinratana, Nonthaneth, Chutiwitoonchai, Nopporn, Castillo, Agnes L., Banlunara, Wijit, Vajragupta, Opa, Rojsitthisak, Pornchai, Rojsitthisak, Pranee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782217/
https://www.ncbi.nlm.nih.gov/pubmed/36559173
http://dx.doi.org/10.3390/pharmaceutics14122680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782217/
https://www.ncbi.nlm.nih.gov/pubmed/36559173
http://dx.doi.org/10.3390/pharmaceutics14122680

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