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Enhanced Nasal Deposition and Anti-Coronavirus Effect of Favipiravir-Loaded Mucoadhesive Chitosan–Alginate Nanoparticles
Favipiravir (FVR) is a repurposed antiviral drug for treating mild to moderate cases of the novel coronavirus disease 2019 (COVID-19). However, its poor solubility and permeability limit its clinical efficacy. To overcome its physicochemical and pharmacokinetic limitations, we statistically designed...
Autores principales: | Alcantara, Khent Primo, Nalinratana, Nonthaneth, Chutiwitoonchai, Nopporn, Castillo, Agnes L., Banlunara, Wijit, Vajragupta, Opa, Rojsitthisak, Pornchai, Rojsitthisak, Pranee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782217/ https://www.ncbi.nlm.nih.gov/pubmed/36559173 http://dx.doi.org/10.3390/pharmaceutics14122680 |
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