Optimising Fluvoxamine Maternal/Fetal Exposure during Gestation: A Pharmacokinetic Virtual Clinical Trials Study

Fluvoxamine plasma concentrations have been shown to decrease throughout pregnancy. CYP2D6 polymorphisms significantly influence these changes. However, knowledge of an optimum dose adjustment according to the CYP2D6 phenotype is still limited. This study implemented a physiologically based pharmaco...

Descripción completa

Detalles Bibliográficos
Autores principales: Burhanuddin, Khairulanwar, Badhan, Raj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782298/
https://www.ncbi.nlm.nih.gov/pubmed/36557319
http://dx.doi.org/10.3390/metabo12121281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782298/
https://www.ncbi.nlm.nih.gov/pubmed/36557319
http://dx.doi.org/10.3390/metabo12121281

Ejemplares similares