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Heat-Induced Conformational Transition Mechanism of Heat Shock Factor 1 Investigated by Tryptophan Probe

[Image: see text] A transcriptional regulatory system called heat shock response (HSR) has been developed in eukaryotic cells to maintain proteome homeostasis under various stresses. Heat shock factor-1 (Hsf1) plays a central role in HSR, mainly by upregulating molecular chaperones as a transcriptio...

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Detalles Bibliográficos
Autores principales: Kawagoe, Soichiro, Kumashiro, Munehiro, Mabuchi, Takuya, Kumeta, Hiroyuki, Ishimori, Koichiro, Saio, Tomohide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782367/
https://www.ncbi.nlm.nih.gov/pubmed/36485006
http://dx.doi.org/10.1021/acs.biochem.2c00492