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Cell contractility and focal adhesion kinase control circumferential arterial stiffness

Arterial stiffening is a hallmark of aging and cardiovascular disease. While it is well established that vascular smooth muscle cells (SMCs) contribute to arterial stiffness by synthesizing and remodeling the arterial extracellular matrix, the direct contributions of SMC contractility and mechanosen...

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Detalles Bibliográficos
Autores principales: Roberts, Emilia, Xu, Tina, Assoian, Richard K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782408/
https://www.ncbi.nlm.nih.gov/pubmed/36222505
http://dx.doi.org/10.1530/VB-22-0013