Cargando…

Cell contractility and focal adhesion kinase control circumferential arterial stiffness

Arterial stiffening is a hallmark of aging and cardiovascular disease. While it is well established that vascular smooth muscle cells (SMCs) contribute to arterial stiffness by synthesizing and remodeling the arterial extracellular matrix, the direct contributions of SMC contractility and mechanosen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Roberts, Emilia, Xu, Tina, Assoian, Richard K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bioscientifica Ltd 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782408/ https://www.ncbi.nlm.nih.gov/pubmed/36222505 http://dx.doi.org/10.1530/VB-22-0013

Ejemplares similares

Arterial stiffness and cardiac dysfunction in Hutchinson–Gilford Progeria Syndrome corrected by inhibition of lysyl oxidase
por: von Kleeck, Ryan, et al.
Publicado: (2021)

Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart
por: Hirth, Sofia, et al.
Publicado: (2016)

Effects of substrate stiffness and actomyosin contractility on coupling between force transmission and vinculin–paxillin recruitment at single focal adhesions
por: Zhou, Dennis W., et al.
Publicado: (2017)

Control of adhesion-dependent cell survival by focal adhesion kinase
Publicado: (1996)

Focal adhesion kinase activity is required for actomyosin contractility-based invasion of cells into dense 3D matrices
por: Mierke, Claudia T., et al.
Publicado: (2017)

Decreased vascular smooth muscle contractility in Hutchinson–Gilford Progeria Syndrome linked to defective smooth muscle myosin heavy chain expression
por: von Kleeck, Ryan, et al.
Publicado: (2021)

Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics
por: Schober, Markus, et al.
Publicado: (2007)

Corrigendum: Focal adhesion kinase activity is required for actomyosin contractility-based invasion of cells into dense 3D matrices
por: Mierke, Claudia T., et al.
Publicado: (2017)

Substrate stiffness governs the initiation of B cell activation by the concerted signaling of PKCβ and focal adhesion kinase
por: Shaheen, Samina, et al.
Publicado: (2017)

The Focal Adhesion: A Regulated Component of Aortic Stiffness
por: Saphirstein, Robert J., et al.
Publicado: (2013)

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions
Publicado: (1996)

Actomyosin contractility and buckling of microtubules in nucleation, growth and disassembling of focal adhesions
por: Palumbo, S., et al.
Publicado: (2022)

Stiffness-dependent motility and proliferation uncoupled by deletion of CD44
por: Razinia, Ziba, et al.
Publicado: (2017)

Focal Adhesion Kinases in Adhesion Structures and Disease
por: Eleniste, Pierre P., et al.
Publicado: (2012)

Focal adhesion kinase-dependent focal adhesion recruitment of SH2 domains directs SRC into focal adhesions to regulate cell adhesion and migration
por: Wu, Jui-Chung, et al.
Publicado: (2015)

Regulation of the Cell Cycle by Focal Adhesion Kinase
por: Zhao, Ji-He, et al.
Publicado: (1998)

Mechanism of Focal Adhesion Kinase Mechanosensing
por: Zhou, Jing, et al.
Publicado: (2015)

Key role for Rac in the early transcriptional response to extracellular matrix stiffness and stiffness-dependent repression of ATF3
por: Dang, Irène, et al.
Publicado: (2023)

The KDEL receptor signalling cascade targets focal adhesion kinase on focal adhesions and invadopodia
por: Ruggiero, Carmen, et al.
Publicado: (2017)

Arthroscopic Circumferential Release for Stiff Reverse Total Shoulder Arthroplasty
por: Aguilar-Gonzalez, Juan, et al.
Publicado: (2020)

Focal adhesion kinase-mediated signaling controls the onset of pancreatic cell differentiation
por: Rodriguez, Uylissa A., et al.
Publicado: (2022)

Requirement of focal adhesion kinase in branching tubulogenesis
por: Wei, Wei-Chun, et al.
Publicado: (2009)

Activation of Rho-kinase and focal adhesion kinase regulates the organization of stress fibers and focal adhesions in the central part of fibroblasts
por: Katoh, Kazuo
Publicado: (2017)

Flotillins Regulate Focal Adhesions by Interacting with α-Actinin and by Influencing the Activation of Focal Adhesion Kinase
por: Banning, Antje, et al.
Publicado: (2018)

The Regulation of Axon Diameter: From Axonal Circumferential Contractility to Activity-Dependent Axon Swelling
por: Costa, Ana Rita, et al.
Publicado: (2018)

Circulating adhesion molecules and arterial stiffness
por: Dogu Kilic, Ismail, et al.
Publicado: (2015)

Increased Stiffness Downregulates Focal Adhesion Kinase Expression in Pancreatic Cancer Cells Cultured in 3D Self-Assembling Peptide Scaffolds
por: Betriu, Nausika, et al.
Publicado: (2022)

Emerging Roles of Focal Adhesion Kinase in Cancer
por: Tai, Yu-Ling, et al.
Publicado: (2015)

Y‐27632, an Inhibitor of Rho‐associated Protein Kinase, Suppresses Tumor Cell Invasion via Regulation of Focal Adhesion and Focal Adhesion Kinase
por: Imamura, Fumio, et al.
Publicado: (2000)

TRPM4 Is a Novel Component of the Adhesome Required for Focal Adhesion Disassembly, Migration and Contractility
por: Cáceres, Mónica, et al.
Publicado: (2015)

Regulation of lamellipodial persistence, adhesion turnover, and motility in macrophages by focal adhesion kinase
por: Owen, Katherine A., et al.
Publicado: (2007)

Protein Kinase C, Focal Adhesions and the Regulation of Cell Migration
por: Fogh, Betina S., et al.
Publicado: (2014)

Targeting focal adhesion kinase in cancer cells and the tumor microenvironment
por: Murphy, James M., et al.
Publicado: (2020)

Focal adhesion kinase is involved in the migration of human osteosarcoma cells
por: Feng, Sitan, et al.
Publicado: (2021)

N-Cadherin Induction by ECM Stiffness and FAK Overrides the Spreading Requirement for Proliferation of Vascular Smooth Muscle Cells
por: Mui, Keeley L., et al.
Publicado: (2015)

Vascular growth responses to chronic arterial occlusion are unaffected by myeloid specific focal adhesion kinase (FAK) deletion
por: Heuslein, Joshua L., et al.
Publicado: (2016)

Demonstration of contractility of circumferential actin bundles and its morphogenetic significance in pigmented epithelium in vitro and in vivo
Publicado: (1981)

Caspase-mediated Cleavage of Focal Adhesion Kinase pp125(FAK) and Disassembly of Focal Adhesions in Human Endothelial Cell Apoptosis
por: Levkau, Bodo, et al.
Publicado: (1998)

Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions
Publicado: (1993)

Focal Adhesion Remodeling Is Crucial for Glucose-Stimulated Insulin Secretion and Involves Activation of Focal Adhesion Kinase and Paxillin
por: Rondas, Dieter, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_5f5v70c5rhonusgv1nepmvdg5h