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Multidrug resistance transporter-1 dysfunction perturbs meiosis and Ca(2+) homeostasis in oocytes

IN BRIEF: Oocyte quality remains the most important and unsolved issue in reproduction. Our data show that multidrug resistance transporters and oocyte mitochondria are involved in determining oocyte quality in a mouse model. ABSTRACT: Multidrug resistance transporter-1 (MDR-1) is a transmembrane AT...

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Detalles Bibliográficos
Autores principales: Nabi, Dalileh, Bosi, Davide, Gupta, Neha, Thaker, Nidhi, Fissore, Rafael, Brayboy, Lynae M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782432/
https://www.ncbi.nlm.nih.gov/pubmed/36215093
http://dx.doi.org/10.1530/REP-22-0192