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Repurposing BCL-2 and Jak 1/2 inhibitors: Cure and treatment of HIV-1 and other viral infections

B cell lymphoma 2 (BCL-2) family proteins are involved in the mitochondrial apoptotic pathway and are key modulators of cellular lifespan, which is dysregulated during human immunodeficiency virus type 1 (HIV-1) and other viral infections, thereby increasing the lifespan of cells harboring virus, in...

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Detalles Bibliográficos
Autores principales: Reece, Monica D., Song, Colin, Hancock, Sarah C., Pereira Ribeiro, Susan, Kulpa, Deanna A., Gavegnano, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782439/
https://www.ncbi.nlm.nih.gov/pubmed/36569952
http://dx.doi.org/10.3389/fimmu.2022.1033672