A Green Blue LED-Driven Two-Liquid-Phase One-Pot Procedure for the Synthesis of Estrogen-Related Quinol Prodrugs

Quinol derivatives of estrogens are effective pro-drugs in steroid replacement therapy. Here, we report that these compounds can be synthesized in one-pot conditions and high yield by blue LED-driven photo-oxygenation of parent estrogens. The oxidation was performed in buffer and eco-certified 2-met...

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Detalles Bibliográficos
Autores principales: De Marchi, Elisa, Botta, Lorenzo, Bizzarri, Bruno Mattia, Saladino, Raffaele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782465/
https://www.ncbi.nlm.nih.gov/pubmed/36558094
http://dx.doi.org/10.3390/molecules27248961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782465/
https://www.ncbi.nlm.nih.gov/pubmed/36558094
http://dx.doi.org/10.3390/molecules27248961

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