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Connexin 30 Deficiency Ameliorates Disease Progression at the Early Phase in a Mouse Model of Amyotrophic Lateral Sclerosis by Suppressing Glial Inflammation

Connexin 30 (Cx30), which forms gap junctions between astrocytes, regulates cell adhesion and migration, and modulates glutamate transport. Cx30 is upregulated on activated astroglia in central nervous system inflammatory lesions, including spinal cord lesions in mutant superoxide dismutase 1 (mSOD1...

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Detalles Bibliográficos
Autores principales: Hashimoto, Yu, Yamasaki, Ryo, Ko, Senri, Matsuo, Eriko, Kobayakawa, Yuko, Masaki, Katsuhisa, Matsuse, Dai, Isobe, Noriko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782489/
https://www.ncbi.nlm.nih.gov/pubmed/36555685
http://dx.doi.org/10.3390/ijms232416046