Lipid–Polymer Hybrid Nanoparticles for mRNA Delivery to Dendritic Cells: Impact of Lipid Composition on Performance in Different Media

To combine the excellent transfection properties of lipids with the high stability of polymeric nanoparticles, we designed a hybrid system with a polymeric core surrounded by a shell of different lipids. The aim is to use this technology for skin vaccination purposes where the transfection of dendri...

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Detalles Bibliográficos
Autores principales: Kliesch, Lena, Delandre, Simon, Gabelmann, Aljoscha, Koch, Marcus, Schulze, Kai, Guzmán, Carlos A., Loretz, Brigitta, Lehr, Claus-Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782540/
https://www.ncbi.nlm.nih.gov/pubmed/36559170
http://dx.doi.org/10.3390/pharmaceutics14122675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782540/
https://www.ncbi.nlm.nih.gov/pubmed/36559170
http://dx.doi.org/10.3390/pharmaceutics14122675

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