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Lipid–Polymer Hybrid Nanoparticles for mRNA Delivery to Dendritic Cells: Impact of Lipid Composition on Performance in Different Media
To combine the excellent transfection properties of lipids with the high stability of polymeric nanoparticles, we designed a hybrid system with a polymeric core surrounded by a shell of different lipids. The aim is to use this technology for skin vaccination purposes where the transfection of dendri...
Autores principales: | Kliesch, Lena, Delandre, Simon, Gabelmann, Aljoscha, Koch, Marcus, Schulze, Kai, Guzmán, Carlos A., Loretz, Brigitta, Lehr, Claus-Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782540/ https://www.ncbi.nlm.nih.gov/pubmed/36559170 http://dx.doi.org/10.3390/pharmaceutics14122675 |
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